Liverpool will look to continue their journey on cloud nine as they entertain Mark Hughes' Southampton at Anfield on Saturday afternoon.
Jurgen Klopp 's men continued their perfect record this season with a thrilling 3-2 Champions League triumph over Ligue 1 champions Paris Saint-Germain in Group C.
The Reds, who along with Chelsea have emerged as the Premier League's early pacesetters, had already notched up five consecutive league victories, including a win at Wembley against Spurs, before their midweek clash against the French giants.
Mark Hughes' Southampton are next in line to attempt to break Liverpool's 100% record, but the Saints will need to improve on their defensive showing last time out.
The Saints threw away a 2-0 lead against Brighton on Monday night to emerge with just a point at St Mary's, but Hughes will hope that his side can rediscover the form that saw them claim a victory against Crystal Palace before the international break.
Liverpool team news
Liverpool forward Roberto Firmino is fit to start against Southampton at Anfield.
The Brazil international was only a substitute for the Champions League victory over Paris St Germain because of an eye injury sustained against Tottenham last weekend.
Fellow forward Dominic Solanke is back after concussion, Divock Origi (ankle) is set to return to training on Sunday while defender Dejan Lovren (hip) has rejoined the squad but will not feature against Saints.
Provisional squad: Alisson, Alexander-Arnold, Gomez, Van Dijk, Robertson, Wijnaldum, Milner, Keita, Salah, Firmino, Mane, Mignolet, Clyne, Matip, Moreno, Henderson, Fabinho, Shaqiri, Solanke.
Southampton team news
Southampton must do without on-loan forward Danny Ings for the Premier League trip to Liverpool.
Ings, who has scored three times this season, is ineligible for the match at Anfield under the terms of his season-long switch from the Reds.
Forward Manolo Gabbiadini faces a late fitness test on a hamstring problem picked up in training, but otherwise Saints boss Mark Hughes has no fresh injury worries.
Provisional Squad: McCarthy, Soares, Vestergaard, Hoedt, Bertrand, Elyounoussi, Lemina, Redmond, Hojbjerg, Long, Austin, Gunn, Yoshida, Targett, Davis, Ward-Prowse, Gabbiadini, Gallagher
Important match stats
Southampton have won just three of their 19 Premier League visits to Anfield (W3 D6 L10), their last victory coming in September 2013.
Liverpool have kept a clean sheet in each of their last four Premier League games against Southampton – the Reds' longest current run in the competition.
Liverpool are looking to start to top-flight campaign with six consecutive wins for the third time in their history, after 1978-79 (finished 1st) and 1990-91 (finished 2nd).
Liverpool are unbeaten in their last 23 Premier League games at Anfield (W15 D8), their best run in the competition since August 2009 (31 games).
Liverpool have kept a clean sheet in each of their last seven Premier League home games; only twice have they had a better run in the competition (9 in February 2007 and 8 in January 2006).
Since the start of last season, Southampton have dropped more points from winning positions than any other current Premier League side (26).
Liverpool's Sadio Mané has scored 48 Premier League goals and could become the seventh African player to reach 50 in the competition (Efan Ekoku, Yakubu, Kanu, Didier Drogba, Emmanuel Adebayor and Yaya Touré).
Danny Ings has netted three goals in his five Premier League games for Southampton, the same number he scored in 14 matches across his three seasons with Liverpool in the competition.
Mohamed Salah was directly involved in four of Liverpool's five Premier League goals against Southampton last season, netting twice at Anfield and both scoring and assisting at St Mary's.
This will be Liverpool manager Jurgen Klopp's 600th league game in charge in his career – his current record is P599 W295 D158 L146.